T cell–mediated vascular dysfunction of human allografts results from IFN-γ dysregulation of NO synthase

Allograft vascular dysfunction predisposes to arteriosclerosis and graft loss. We examined how dysfunction develops in transplanted human arteries in response to circulating allogeneic T cells in vivo using immunodeficient murine hosts. Within 7–9 days, transplanted arteries developed endothelial ce...

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Hlavní autoři: Koh, Kian Peng, Wang, Yinong, Yi, Tai, Shiao, Stephen L., Lorber, Marc I., Sessa, William C., Tellides, George, Pober, Jordan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2004
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC516264/
https://ncbi.nlm.nih.gov/pubmed/15372109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421767
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