Amelioration of Human Allograft Arterial Injury by Atorvastatin or Simvastatin Correlates with Reduction of Interferon-γ Production by Infiltrating T Cells

BACKGROUND: Graft arteriosclerosis (GA) is an important factor limiting long-term outcomes after organ transplantation. We have used a chimeric humanized mouse system to model this arteriopathy in human vessels and found the morphologic and functional changes of experimental GA to be interferon (IFN...

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Main Authors: Yi, Tai, Rao, Deepak A., Tang, Paul C.Y., Wang, Yinong, Cuchara, Lisa A., Bothwell, Alfred L.M., Colangelo, Christopher M., Tellides, George, Pober, Jordan S., Lorber, Marc I.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650813/
https://ncbi.nlm.nih.gov/pubmed/18791454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e318183eefa
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