Interleukin-17 and Interferon-γ are Produced Concomitantly by Human Coronary Artery-Infiltrating T Cells and Act Synergistically on Vascular Smooth Muscle Cells

BACKGROUND: Atherosclerosis is an inflammatory disease in which interferon (IFN)-γ, the signature cytokine of Th1 cells, plays a central role. We investigated whether interleukin (IL)-17, the signature cytokine of Th17 cells, is also associated with human coronary atherosclerosis. METHODS AND RESULT...

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Hoofdauteurs: Eid, Raymond E., Rao, Deepak A., Zhou, Jing, Lo, Sheng-fu L., Ranjbaran, Hooman, Gallo, Amy, Sokol, Seth I., Pfau, Steven, Pober, Jordan S., Tellides, George
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898514/
https://ncbi.nlm.nih.gov/pubmed/19255340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.827618
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