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AIP1 prevents graft arteriosclerosis by inhibiting IFN-γ-dependent smooth muscle cell proliferation and intimal expansion

BACKGROUND: ASK1-interacting protein-1 (AIP1), a Ras GTPase-activating protein family member, is highly expressed in endothelial cells (EC) and vascular smooth muscle cells (VSMC). The role of AIP1 in VSMC and VSMC-proliferative disease is not known. We employed mouse graft arteriosclerosis models c...

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Bibliographische Detailangaben
Hauptverfasser: Yu, Luyang, Qin, Lingfeng, Zhang, Haifeng, He, Yun, Chen, Hong, Pober, Jordan S., Tellides, George, Min, Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227522/
https://ncbi.nlm.nih.gov/pubmed/21700930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.248245
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