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The link between IFN-γ and allograft arteriopathy: is the answer NO?

Vascularized organ transplants often fail because of smooth muscle cell migration and proliferation in the intima of graft arteries, leading to progressive lumenal narrowing and resultant ischemic damage. Graft arterial disease is caused by IFN-γ secreted by alloreactive T cells. New evidence indica...

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Autori principali: Mitchell, Richard N., Lichtman, Andrew H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC516268/
https://ncbi.nlm.nih.gov/pubmed/15372099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422927
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