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Structural insight into the necessary conformational changes of modular nonribosomal peptide synthetases

Nonribosomal peptide synthetases (NRPSs) catalyze the assembly line biosynthesis of peptide natural products that play important roles in microbial signaling and communication. These multidomain enzymes use an integrated carrier protein that delivers the growing peptide to the catalytic domains, req...

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Détails bibliographiques
Publié dans:Curr Opin Chem Biol
Auteur principal: Gulick, Andrew M.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161630/
https://ncbi.nlm.nih.gov/pubmed/27676239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2016.09.005
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