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Structures of Two Distinct Conformations of holo-Nonribosomal Peptide Synthetases
Many important natural products are produced by multidomain nonribosomal peptide synthetases (NRPSs)(1–4). During synthesis, intermediates are covalently bound to integrated carrier domains and transported to neighboring catalytic domains in an assembly line fashion(5). Understanding the structural...
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| Yayımlandı: | Nature |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843164/ https://ncbi.nlm.nih.gov/pubmed/26762461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16163 |
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