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Structure determination of the functional domain interaction of a chimeric nonribosomal peptide synthetase from a challenging crystal with noncrystallographic translational symmetry

The nonribosomal peptide synthetases (NRPSs) are a family of modular proteins that contain multiple catalytic domains joined in a single protein. Together, these domains work to produce chemically diverse peptides, including compounds with antibiotic activity or that play a role in iron acquisition....

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Bibliographic Details
Main Authors: Sundlov, Jesse A., Gulick, Andrew M.
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727328/
https://ncbi.nlm.nih.gov/pubmed/23897471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444913009372
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