HER2 expression identifies dynamic functional states within circulating breast cancer cells

Circulating tumor cells (CTCs) in women with advanced estrogen receptor-positive/HER2-negative breast cancer acquire a HER2-positive subpopulation following multiple courses of therapy(1,2). In contrast to HER2-amplified primary breast cancer, which is highly sensitive to HER2-targeted therapy, the...

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Publicat a:Nature
Autors principals: Jordan, Nicole Vincent, Bardia, Aditya, Wittner, Ben S., Benes, Cyril, Ligorio, Matteo, Zheng, Yu, Yu, Min, Sundaresan, Tilak K., Licausi, Joseph A., Desai, Rushil, O’Keefe, Ryan M., Ebright, Richard Y., Boukhali, Myriam, Sil, Srinjoy, Onozato, Maristela L., Iafrate, Anthony J., Kapur, Ravi, Sgroi, Dennis, Ting, David T., Toner, Mehmet, Ramaswamy, Sridhar, Haas, Wilhelm, Maheswaran, Shyamala, Haber, Daniel A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161614/
https://ncbi.nlm.nih.gov/pubmed/27556950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19328
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