A microfluidic device for label-free, physical capture of circulating tumor cell-clusters

Cancer cells metastasize through the bloodstream either as single migratory circulating tumor cells (CTCs) or as multicellular groupings (CTC-clusters). Existing technologies for CTC enrichment are designed primarily to isolate single CTCs, and while CTC-clusters are detectable in some cases, their...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Sarioglu, A. Fatih, Aceto, Nicola, Kojic, Nikola, Donaldson, Maria C., Zeinali, Mahnaz, Hamza, Bashar, Engstrom, Amanda, Zhu, Huili, Sundaresan, Tilak K., Miyamoto, David T., Luo, Xi, Bardia, Aditya, Wittner, Ben S., Ramaswamy, Sridhar, Shioda, Toshi, Ting, David T., Stott, Shannon L., Kapur, Ravi, Maheswaran, Shyamala, Haber, Daniel A., Toner, Mehmet
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490017/
https://ncbi.nlm.nih.gov/pubmed/25984697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3404
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