A microfluidic device for label-free, physical capture of circulating tumor cell-clusters

Cancer cells metastasize through the bloodstream either as single migratory circulating tumor cells (CTCs) or as multicellular groupings (CTC-clusters). Existing technologies for CTC enrichment are designed primarily to isolate single CTCs, and while CTC-clusters are detectable in some cases, their...

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發表在:Nat Methods
Main Authors: Sarioglu, A. Fatih, Aceto, Nicola, Kojic, Nikola, Donaldson, Maria C., Zeinali, Mahnaz, Hamza, Bashar, Engstrom, Amanda, Zhu, Huili, Sundaresan, Tilak K., Miyamoto, David T., Luo, Xi, Bardia, Aditya, Wittner, Ben S., Ramaswamy, Sridhar, Shioda, Toshi, Ting, David T., Stott, Shannon L., Kapur, Ravi, Maheswaran, Shyamala, Haber, Daniel A., Toner, Mehmet
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490017/
https://ncbi.nlm.nih.gov/pubmed/25984697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3404
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