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Chronic Infection Depletes Hematopoietic Stem Cells Through Stress-Induced Terminal Differentiation

Chronic infections affect a third of the world’s population and can cause bone marrow suppression, a severe condition that increases mortality from infection. To uncover the basis for infection-associated bone marrow suppression, we conducted repeated infection of WT mice with Mycobacterium avium. A...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Matatall, Katie A., Jeong, Mira, Chen, Siyi, Sun, Deqiang, Chen, Fengju, Mo, Qianxing, Kimmel, Marek, King, Katherine Y.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161248/
https://ncbi.nlm.nih.gov/pubmed/27926863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.031
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