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Type II Interferon Promotes Differentiation of Myeloid-Biased Hematopoietic Stem Cells

Interferon gamma (IFNγ) promotes cell division of hematopoietic stem cells (HSCs) without affecting the total HSC number. We postulated that IFNγ stimulates differentiation of HSCs as part of the innate immune response. Here we report that type II interferon signaling is required, both at baseline a...

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Bibliografiset tiedot
Päätekijät: Matatall, Katie A., Shen, Ching-Chieh, Challen, Grant A., King, Katherine Y.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198460/
https://ncbi.nlm.nih.gov/pubmed/25078851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1799
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