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Type II Interferon Promotes Differentiation of Myeloid-Biased Hematopoietic Stem Cells

Interferon gamma (IFNγ) promotes cell division of hematopoietic stem cells (HSCs) without affecting the total HSC number. We postulated that IFNγ stimulates differentiation of HSCs as part of the innate immune response. Here we report that type II interferon signaling is required, both at baseline a...

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Detalhes bibliográficos
Principais autores: Matatall, Katie A., Shen, Ching-Chieh, Challen, Grant A., King, Katherine Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198460/
https://ncbi.nlm.nih.gov/pubmed/25078851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1799
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