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Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2
During chronic infection, the inflammatory cytokine interferon gamma (IFNγ) damages hematopoietic stem cells (HSCs) by disrupting quiescence and promoting excessive terminal differentiation. However, the mechanism by which IFNγ hinders HSC quiescence remains undefined. Using intravital 3-dimensional...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7816211/ https://ncbi.nlm.nih.gov/pubmed/33357430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108530 |
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