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Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
BACKGROUND: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistically confident dissimilarities between (1) MSA position and a set of predicted residue frequencies, and (2) between two MSA...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516024/ https://ncbi.nlm.nih.gov/pubmed/15296518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-5-106 |
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