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Exploring dynamics of protein structure determination and homology-based prediction to estimate the number of superfamilies and folds

BACKGROUND: As tertiary structure is currently available only for a fraction of known protein families, it is important to assess what parts of sequence space have been structurally characterized. We consider protein domains whose structure can be predicted by sequence similarity to proteins with so...

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Detalhes bibliográficos
Main Authors: Sadreyev, Ruslan I, Grishin, Nick V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1444916/
https://ncbi.nlm.nih.gov/pubmed/16549009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-6-6
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