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Exploring dynamics of protein structure determination and homology-based prediction to estimate the number of superfamilies and folds

BACKGROUND: As tertiary structure is currently available only for a fraction of known protein families, it is important to assess what parts of sequence space have been structurally characterized. We consider protein domains whose structure can be predicted by sequence similarity to proteins with so...

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Autores principales: Sadreyev, Ruslan I, Grishin, Nick V
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1444916/
https://ncbi.nlm.nih.gov/pubmed/16549009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-6-6
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