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Defining and predicting structurally conserved regions in protein superfamilies

Motivation: The structures of homologous proteins are generally better conserved than their sequences. This phenomenon is demonstrated by the prevalence of structurally conserved regions (SCRs) even in highly divergent protein families. Defining SCRs requires the comparison of two or more homologous...

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Detalhes bibliográficos
Main Authors: Huang, Ivan K., Pei, Jimin, Grishin, Nick V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546793/
https://ncbi.nlm.nih.gov/pubmed/23193223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts682
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