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Defining and predicting structurally conserved regions in protein superfamilies

Motivation: The structures of homologous proteins are generally better conserved than their sequences. This phenomenon is demonstrated by the prevalence of structurally conserved regions (SCRs) even in highly divergent protein families. Defining SCRs requires the comparison of two or more homologous...

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Hlavní autoři: Huang, Ivan K., Pei, Jimin, Grishin, Nick V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546793/
https://ncbi.nlm.nih.gov/pubmed/23193223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts682
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