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Accurate statistical model of comparison between multiple sequence alignments

Comparison of multiple protein sequence alignments (MSA) reveals unexpected evolutionary relations between protein families and leads to exciting predictions of spatial structure and function. The power of MSA comparison critically depends on the quality of statistical model used to rank the similar...

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Autors principals: Sadreyev, Ruslan I., Grishin, Nick V.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367703/
https://ncbi.nlm.nih.gov/pubmed/18285364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn065
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