Inducible cytochrome P450 activities in renal glomerular mesangial cells: biochemical basis for antagonistic interactions among nephrocarcinogenic polycyclic aromatic hydrocarbons

BACKGROUND: Benzo(a)pyrene (BaP), anthracene (ANTH) and chrysene (CHRY) are polynuclear aromatic hydrocarbons (PAHs) implicated in renal toxicity and carcinogenesis. These PAHs elicit cell type-specific effects that help predict toxicity outcomes in vitro and in vivo. While BaP and ANTH selectively...

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Autors principals: Falahatpisheh, MH, Kerzee, JK, Metz, RP, Donnelly, KC, Ramos, KS
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC516019/
https://ncbi.nlm.nih.gov/pubmed/15315710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-3-12
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