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Interaction of smoking, uptake of polycyclic aromatic hydrocarbons, and cytochrome P450IA2 activity among foundry workers.

An increased lung cancer risk has been described among foundry workers. Polycyclic aromatic hydrocarbons (PAHs) and silica are possible aetiological factors. This study describes a urinary PAH metabolite, 1-hydroxypyrene (hpU), as well as the degree of cytochrome P450IA2 activity/induction as reflec...

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Détails bibliographiques
Auteurs principaux: Sherson, D, Sigsgaard, T, Overgaard, E, Loft, S, Poulsen, H E, Jongeneelen, F J
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1012094/
https://ncbi.nlm.nih.gov/pubmed/1554617
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