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Identification of mitochondrial cytochrome P450 induced in response to polycyclic aromatic hydrocarbons in the mummichog (Fundulus heteroclitus)

Increasing evidence suggests that polycyclic aromatic hydrocarbons (PAHs) such as benzo[a]pyrene (BaP) are localized to the mitochondria. Because the toxic effects of many PAHs are the result of metabolism by cytochrome P4501A (CYP1A), it is important to investigate whether active forms of these enz...

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Detalhes bibliográficos
Main Authors: Jung, Dawoon, Di Giulio, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787737/
https://ncbi.nlm.nih.gov/pubmed/19758578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpc.2009.09.003
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