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A multi-step model for facilitated unwinding of the yeast U4/U6 RNA duplex

The small nuclear RNA (snRNA) components of the spliceosome undergo many conformational rearrangements during its assembly, catalytic activation and disassembly. The U4 and U6 snRNAs are incorporated into the spliceosome as a base-paired complex within the U4/U6.U5 small nuclear ribonucleoprotein (t...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Rodgers, Margaret L., Didychuk, Allison L., Butcher, Samuel E., Brow, David A., Hoskins, Aaron A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159527/
https://ncbi.nlm.nih.gov/pubmed/27484481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw686
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