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Assessing the similarity of ligand binding conformations with the Contact Mode Score

Structural and computational biologists often need to measure the similarity of ligand binding conformations. The commonly used root-mean-square deviation (RMSD) is not only ligand-size dependent, but also may fail to capture biologically meaningful binding features. To address these issues, we deve...

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Detalhes bibliográficos
Publicado no:Comput Biol Chem
Main Authors: Ding, Yun, Fang, Ye, Moreno, Juana, Ramanujam, J., Jarrell, Mark, Brylinski, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159245/
https://ncbi.nlm.nih.gov/pubmed/27620381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiolchem.2016.08.007
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