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Scoring Confidence Index: Statistical Evaluation of Ligand Binding Mode Predictions

Protein-ligand docking programs can generate a large number of possible binding orientations for each ligand candidate. The challenge is to identify the orientations closest to the native binding mode using a scoring method. Many different scoring functions have been developed for protein-ligand sco...

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Bibliografiske detaljer
Main Authors: Zavodszky, Maria I., Stumpff-Kane, Andrew W., Lee, David J., Feig, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720621/
https://ncbi.nlm.nih.gov/pubmed/19153808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-008-9258-8
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