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Aromatic interactions at the ligand-protein interface: Implications for the development of docking scoring functions

The ability to design and fine-tune non-covalent interactions between organic ligands and proteins is indispensable to rational drug development. Aromatic stacking has long been recognized as one of the key constituents of ligand-protein interfaces. In this communication, we employ a two-parameter g...

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Vydáno v:Chem Biol Drug Des
Hlavní autor: Brylinski, Michal
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818208/
https://ncbi.nlm.nih.gov/pubmed/28816025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13084
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