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Exon junction complex proteins bind nascent transcripts independently of pre-mRNA splicing in Drosophila melanogaster

Although it is currently understood that the exon junction complex (EJC) is recruited on spliced mRNA by a specific interaction between its central protein, eIF4AIII, and splicing factor CWC22, we found that eIF4AIII and the other EJC core proteins Y14 and MAGO bind the nascent transcripts of not on...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Choudhury, Subhendu Roy, Singh, Anand K, McLeod, Tina, Blanchette, Marco, Jang, Boyun, Badenhorst, Paul, Kanhere, Aditi, Brogna, Saverio
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158136/
https://ncbi.nlm.nih.gov/pubmed/27879206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19881
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