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Transcriptome-wide modulation of splicing by the exon junction complex

BACKGROUND: The exon junction complex (EJC) is a dynamic multi-protein complex deposited onto nuclear spliced mRNAs upstream of exon-exon junctions. The four core proteins, eIF4A3, Magoh, Y14 and MLN51, are stably bound to mRNAs during their lifecycle, serving as a binding platform for other nuclear...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Wang, Zhen, Murigneux, Valentine, Le Hir, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268817/
https://ncbi.nlm.nih.gov/pubmed/25476502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0551-7
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