Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing

Recursive splicing (RS) starts by defining an “RS-exon,” which is then spliced to the preceding exon, thus creating a recursive 5′ splice site (RS-5ss). Previous studies focused on cryptic RS-exons, and now we find that the exon junction complex (EJC) represses RS of hundreds of annotated, mainly co...

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Pubblicato in:Mol Cell
Autori principali: Blazquez, Lorea, Emmett, Warren, Faraway, Rupert, Pineda, Jose Mario Bello, Bajew, Simon, Gohr, Andre, Haberman, Nejc, Sibley, Christopher R., Bradley, Robert K., Irimia, Manuel, Ule, Jernej
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224609/
https://ncbi.nlm.nih.gov/pubmed/30388411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.09.033
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