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Splicing enhances translation in mammalian cells: an additional function of the exon junction complex

In mammalian cells, spliced mRNAs yield greater quantities of protein per mRNA molecule than do otherwise identical mRNAs not made by splicing. This increased translational yield correlates with enhanced cytoplasmic polysome association of spliced mRNAs, and is attributable to deposition of exon jun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nott, Ajit, Le Hir, Hervé, Moore, Melissa J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC324426/
https://ncbi.nlm.nih.gov/pubmed/14752011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1163204
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