Exon junction complex proteins bind nascent transcripts independently of pre-mRNA splicing in Drosophila melanogaster

Although it is currently understood that the exon junction complex (EJC) is recruited on spliced mRNA by a specific interaction between its central protein, eIF4AIII, and splicing factor CWC22, we found that eIF4AIII and the other EJC core proteins Y14 and MAGO bind the nascent transcripts of not on...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Choudhury, Subhendu Roy, Singh, Anand K, McLeod, Tina, Blanchette, Marco, Jang, Boyun, Badenhorst, Paul, Kanhere, Aditi, Brogna, Saverio
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
Assuntos:
Genes and Chromosomes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158136/
https://ncbi.nlm.nih.gov/pubmed/27879206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19881
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