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Incorporating exon–exon junction reads enhances differential splicing detection

Abstract Background RNA sequencing (RNA-seq) is a gold standard technology for studying gene and transcript expression. Different transcripts from the same gene are usually determined by varying combinations of exons within the gene, formed by splicing events. One method of studying differential alt...

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Autores principales: Mai T. Pham, Michael J. G. Milevskiy, Jane E. Visvader, Yunshun Chen
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2025-07-01
Colección:BMC Bioinformatics
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Acceso en línea:https://doi.org/10.1186/s12859-025-06210-4
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