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Inhibition of cAMP-Dependent PKA Activates β(2)-Adrenergic Receptor Stimulation of Cytosolic Phospholipase A(2) via Raf-1/MEK/ERK and IP(3)-Dependent Ca(2+) Signaling in Atrial Myocytes
We previously reported in atrial myocytes that inhibition of cAMP-dependent protein kinase (PKA) by laminin (LMN)-integrin signaling activates β(2)-adrenergic receptor (β(2)-AR) stimulation of cytosolic phospholipase A(2) (cPLA(2)). The present study sought to determine the signaling mechanisms by w...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5158063/ https://ncbi.nlm.nih.gov/pubmed/27977772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168505 |
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