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Phenylephrine acts via IP(3)-dependent intracellular NO release to stimulate L-type Ca(2+) current in cat atrial myocytes
This study determined the effects of α(1)-adrenergic receptor (α(1)-AR) stimulation by phenylephrine (PE) on L-type Ca(2+) current (I(Ca,L)) in cat atrial myocytes. PE (10 μm) reversibly increased I(Ca,L) (51.3%; n = 40) and shifted peak I(Ca,L) activation voltage by −10 mV. PE-induced stimulation o...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1474159/ https://ncbi.nlm.nih.gov/pubmed/15946966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.090035 |
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