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Laminin acts via focal adhesion kinase/phosphatidylinositol-3′ kinase/protein kinase B to down-regulate β(1)-adrenergic receptor signalling in cat atrial myocytes
We previously reported that short-term (2 h) plating of cat atrial myocytes on the extracellular matrix protein, laminin (LMN) decreases adenylate cyclase activity and β(1)-adrenergic receptor (β(1)-AR) stimulation of L-type Ca(2+) current (I(Ca,L)). The present study sought to determine whether LMN...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670079/ https://ncbi.nlm.nih.gov/pubmed/19064616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.163824 |
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