Laminin acts via focal adhesion kinase/phosphatidylinositol-3′ kinase/protein kinase B to down-regulate β(1)-adrenergic receptor signalling in cat atrial myocytes

We previously reported that short-term (2 h) plating of cat atrial myocytes on the extracellular matrix protein, laminin (LMN) decreases adenylate cyclase activity and β(1)-adrenergic receptor (β(1)-AR) stimulation of L-type Ca(2+) current (I(Ca,L)). The present study sought to determine whether LMN...

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Detalhes bibliográficos
Main Authors: Wang, Y G, Ji, X, Pabbidi, M, Samarel, A M, Lipsius, S L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Cellular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670079/
https://ncbi.nlm.nih.gov/pubmed/19064616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.163824
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