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Identification of Human Cathelicidin Peptide LL-37 as a Ligand for Macrophage Integrin α(M)β(2) (Mac-1, CD11b/CD18) that Promotes Phagocytosis by Opsonizing Bacteria
LL-37, a cationic antimicrobial peptide, has numerous immune-modulating effects. However, the identity of a receptor(s) mediating the responses in immune cells remains uncertain. We have recently demonstrated that LL-37 interacts with the α(M)I-domain of integrin α(M)β(2) (Mac-1), a major receptor o...
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| Pubblicato in: | Res Rep Biochem |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5157691/ https://ncbi.nlm.nih.gov/pubmed/27990411 |
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