FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors

BACKGROUND: About 10–15% of adult, and most pediatric, gastrointestinal stromal tumors (GIST) lack mutations in KIT, PDGFRA, SDHx, or RAS pathway components (KRAS, BRAF, NF1). The identification of additional mutated genes in this rare subset of tumors can have important clinical benefit to identify...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Transl Med
Main Authors: Shi, Eileen, Chmielecki, Juliann, Tang, Chih-Min, Wang, Kai, Heinrich, Michael C., Kang, Guhyun, Corless, Christopher L., Hong, David, Fero, Katherine E., Murphy, James D., Fanta, Paul T., Ali, Siraj M., De Siena, Martina, Burgoyne, Adam M., Movva, Sujana, Madlensky, Lisa, Heestand, Gregory M., Trent, Jonathan C., Kurzrock, Razelle, Morosini, Deborah, Ross, Jeffrey S., Harismendy, Olivier, Sicklick, Jason K.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157084/
https://ncbi.nlm.nih.gov/pubmed/27974047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1075-6
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki