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Myofilament Calcium Sensitivity: Mechanistic Insight into TnI Ser-23/24 and Ser-150 Phosphorylation Integration

Troponin I (TnI) is a major regulator of cardiac muscle contraction and relaxation. During physiological and pathological stress, TnI is differentially phosphorylated at multiple residues through different signaling pathways to match cardiac function to demand. The combination of these TnI phosphory...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Salhi, Hussam E., Hassel, Nathan C., Siddiqui, Jalal K., Brundage, Elizabeth A., Ziolo, Mark T., Janssen, Paul M. L., Davis, Jonathan P., Biesiadecki, Brandon J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156683/
https://ncbi.nlm.nih.gov/pubmed/28018230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00567
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