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The role of gigaxonin in the degradation of the glial-specific intermediate filament protein GFAP
Alexander disease (AxD) is a primary genetic disorder of astrocytes caused by dominant mutations in the gene encoding the intermediate filament (IF) protein GFAP. This disease is characterized by excessive accumulation of GFAP, known as Rosenthal fibers, within astrocytes. Abnormal GFAP aggregation...
Shranjeno v:
| izdano v: | Mol Biol Cell |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5156539/ https://ncbi.nlm.nih.gov/pubmed/27798231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0362 |
| Oznake: |
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