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Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP

Alexander disease (AxD) is a neurodegenerative disease caused by heterozygous mutations in the GFAP gene, which encodes the major intermediate filament protein of astrocytes. This disease is characterized by the accumulation of cytoplasmic protein aggregates, known as Rosenthal fibers. Antibodies sp...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lin, Ni-Hsuan, Messing, Albee, Perng, Ming-Der
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503259/
https://ncbi.nlm.nih.gov/pubmed/28700643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180694
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