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Functional Site Discovery in a Sulphur Metabolism Enzyme Using Directed Evolution
In human pathogens, the sulphate assimilation pathway provides reduced sulphur for biosynthesis of essential metabolites including cysteine and low-molecular weight thiol compounds. Sulfonucleotide reductases (SRs) catalyze the first committed step of sulphate reduction. In this reaction, activated...
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| Publicado en: | Chembiochem |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5155445/ https://ncbi.nlm.nih.gov/pubmed/27411165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600264 |
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