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Efficient microwave-assisted solid phase coupling of nucleosides, small library generation and mild conditions for release of nucleoside derivatives

Nucleosides are essential bio-molecules that participate in a wide array of biological processes involved in maintaining physiologic homeostasis. Recent efforts geared towards the synthesis of nucleoside analogues and development of nucleoside combinatorial libraries using solid phase synthesis has...

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Autors principals: Paritala, Hanumantharao, Suzuki, Yuta, Carroll, Kate S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684988/
https://ncbi.nlm.nih.gov/pubmed/23794759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.01.109
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