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Population History and Natural Selection Shape Patterns of Genetic Variation in 132 Genes

Identifying regions of the human genome that have been targets of natural selection will provide important insights into human evolutionary history and may facilitate the identification of complex disease genes. Although the signature that natural selection imparts on DNA sequence variation is diffi...

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Detalhes bibliográficos
Main Authors: Akey, Joshua M, Eberle, Michael A, Rieder, Mark J, Carlson, Christopher S, Shriver, Mark D, Nickerson, Deborah A, Kruglyak, Leonid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC515367/
https://ncbi.nlm.nih.gov/pubmed/15361935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020286
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