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Sequence Variation and Linkage Disequilibrium in the Human T-Cell Receptor β (TCRB) Locus

The T-cell receptor (TCR) plays a central role in the immune system, and >90% of human T cells present a receptor that consists of the α TCR subunit (TCRA) and the β subunit (TCRB). Here we report an analysis of 63 variable genes (BV), spanning 553 kb of TCRB that yielded 279 single-nucleotide po...

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Bibliographische Detailangaben
Hauptverfasser: Subrahmanyan, Lakshman, Eberle, Michael A., Clark, Andrew G., Kruglyak, Leonid, Nickerson, Deborah A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Human Genetics 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235310/
https://ncbi.nlm.nih.gov/pubmed/11438886
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