Allele Frequency Matching Between SNPs Reveals an Excess of Linkage Disequilibrium in Genic Regions of the Human Genome

Significant interest has emerged in mapping genetic susceptibility for complex traits through whole-genome association studies. These studies rely on the extent of association, i.e., linkage disequilibrium (LD), between single nucleotide polymorphisms (SNPs) across the human genome. LD describes the...

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Autores principales: Eberle, Michael A, Rieder, Mark J, Kruglyak, Leonid, Nickerson, Deborah A
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2006
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560400/
https://ncbi.nlm.nih.gov/pubmed/16965180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020142
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