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Allele Frequency Matching Between SNPs Reveals an Excess of Linkage Disequilibrium in Genic Regions of the Human Genome

Significant interest has emerged in mapping genetic susceptibility for complex traits through whole-genome association studies. These studies rely on the extent of association, i.e., linkage disequilibrium (LD), between single nucleotide polymorphisms (SNPs) across the human genome. LD describes the...

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Hlavní autoři: Eberle, Michael A, Rieder, Mark J, Kruglyak, Leonid, Nickerson, Deborah A
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560400/
https://ncbi.nlm.nih.gov/pubmed/16965180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020142
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