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Allele Frequency Matching Between SNPs Reveals an Excess of Linkage Disequilibrium in Genic Regions of the Human Genome

Significant interest has emerged in mapping genetic susceptibility for complex traits through whole-genome association studies. These studies rely on the extent of association, i.e., linkage disequilibrium (LD), between single nucleotide polymorphisms (SNPs) across the human genome. LD describes the...

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書誌詳細
主要な著者: Eberle, Michael A, Rieder, Mark J, Kruglyak, Leonid, Nickerson, Deborah A
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560400/
https://ncbi.nlm.nih.gov/pubmed/16965180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020142
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