Population History and Natural Selection Shape Patterns of Genetic Variation in 132 Genes

Identifying regions of the human genome that have been targets of natural selection will provide important insights into human evolutionary history and may facilitate the identification of complex disease genes. Although the signature that natural selection imparts on DNA sequence variation is diffi...

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Main Authors: Akey, Joshua M, Eberle, Michael A, Rieder, Mark J, Carlson, Christopher S, Shriver, Mark D, Nickerson, Deborah A, Kruglyak, Leonid
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2004
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC515367/
https://ncbi.nlm.nih.gov/pubmed/15361935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020286
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