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Probing Small Molecule Binding to Unfolded Polyprotein Based on its Elasticity and Refolding
Unfolded protein, a disordered structure found before folding of newly synthesized protein or after protein denaturation, is a substrate for binding by many cellular factors such as heat-stable proteins, chaperones, and many small molecules. However, it is challenging to directly probe such interact...
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| Izdano u: | Biophys J |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5153558/ https://ncbi.nlm.nih.gov/pubmed/27926836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.10.031 |
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