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A Nucleophilic Strategy for Enantioselective Intermolecular α-Amination: Access to Enantioenriched α-Arylamino Ketones

The enantioselective addition of anilines to azoalkenes was accomplished through the use of a chiral phosphoric acid catalyst. The resulting α-arylamino hydrazones were obtained in good yields and excellent enantioselectivities and provide access to enantioenriched α-arylamino ketones. A serendipito...

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Bibliografiska uppgifter
I publikationen:J Am Chem Soc
Huvudupphovsmän: Miles, Dillon H., Guasch, Joan, Toste, F. Dean
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152760/
https://ncbi.nlm.nih.gov/pubmed/26066512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04518
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