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Strategies for the Catalytic Enantioselective Synthesis of α-Trifluoromethyl Amines

The exploitation of the α-trifluoromethylamino group as an amide surrogate in peptidomimetics and drug candidates has been on the rise. In a large number of these cases, this moiety bears stereochemistry with the stereochemical identity having important consequences on numerous molecular properties,...

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Detalhes bibliográficos
Publicado no:ACS Catal
Main Authors: Onyeagusi, Chibueze I., Malcolmson, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302206/
https://ncbi.nlm.nih.gov/pubmed/34306806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c03569
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